Kenneth Cain

• Ma, J., Bruce, T.J., Sudheesh, P.S., Knupp, C., Loch, T.P., Faisal, M. and Cain, K.D. 2018. Assessment of cross-protection to heterologous strains of Flavobacterium psychrophilum following vaccination with a live-attenuated coldwater disease immersion vaccine. Journal of Fish Diseases (In Press)
• Nguyen P, Sudheesh, P.S. Sinnesael, M., Thomas, A. Haman, K. and Cain, K.D. 2018. Rapid Detection and Monitoring of Flavobacterium psychrophilum in Water by Using a Handheld Field-Portable qPCR System. North American Journal of Aquatic Animal Health (In Press)
• Terrazas, M.M., Anderson, C.L. Jacobs, S.J. and Cain, K.D. 2018. Identification of Two Pathogenic Aeromonas Species Isolated during Production Related Epizootics from Juvenile Burbot Lota lota maculosa. North American Journal of Aquatic Animal Health 30 (3) doi:10.1002/aah.10023
• Jaing, M.N, Fan, Yuding, Cain, K., Zeng, L. 2018. Development of cross-priming amplification coupled with vertical flow visualization for rapid detection of infectious spleen and kidney necrosis virus (ISKNV) in mandarin fish, Siniperca chuatsi. Journal of Virological Methods 253, 38-42
• Terrazas, M.M., Adams, J.R., Sudheesh, P. and Cain, K.D. 2018. Effects of Diel Temperature Fluctuation on Growth, Stress Response, and Immune Function of Burbot. Transactions of the American Fisheries Society, Volume 146, 996 – 1007
• Hutson, K.S. and Cain, K.D. Pathogens and Parasites, in: Aquaculture: Farming Aquatic Animals and Plants. Volume 3, (ed) Southgate, P.C.) Wiley-Blackwell publishing. (In Press)
• Sudheesh, P.S. and Cain, K.D. 2017. Prospects and challenges of developing and commercializing immersion vaccines for aquaculture. International Biology Review 1(1): 1-20
• Villasantea, A.,Powell, M.S., Murdoch, G.K., Overturf, K., Cain, K., Wacyke, J., Hardy, R.W. 2016. Effect of anthocyanidins on myogenic differentiation 1 in induced and non-induced primary myoblasts from rainbow trout (Oncorhynchus mykiss). Comparative Biochemistry and Physiology Part B 196–197: 102–108
• Sudheesh, P.S. and Cain, K.D. 2016. Optimization of efficacy of a live attenuated Flavobacterium psychrophilum immersion vaccine. Fish & Shellfish Immunology 56: 169-180
• Ashton, N.K., Campbell, M.R., Anders, P.J., Powell, M.S. and Cain, K.D. 2016. Evaluating Microsatellite Markers for Parentage-Based Tagging of Hatchery Burbot. Northwest Science, 90(3):249-259
• Sudheesh, P.S., Zimmerman, J.K. and Cain, K.D. 2016. Dietary effects on immunity, stress, and efficacy of two live attenuated Flavobacterium psychrophilum vaccine formulations. Aquaculture 454 35-43
• Ghosh, B., Cain, K.D., Nowak, B.F. and Bridle, A.R. 2016. Microencapsulation of a putative probiotic Enterobacter species, C6-6, to protect rainbow trout, Oncorhynchus mykiss (Walbaum), against bacterial coldwater disease. Journal of Fish Diseases 39(1):1-11
• Karol Gliniewicz, Mark Wildung, Lisa H. Orfe, Gregory D. Wiens, Kenneth D. Cain, Kevin K. Lahmers, Kevin R. Snekvik and Douglas R. Call. 2015. Potential mechanisms of attenuation for rifampicin-passaged strains of Flavobacterium psychrophilum. BMC Microbiology 15:179
• Long, A., Call, D.R. and Cain, K.D. 2015. Comparison of quantitative PCR and ELISA for detection and quantification of Flavobacterium psychrophilum in salmonid broodstock. Diseases of Aquatic Organism 115: 139–146
• Ghosh, B., Bridle, A.R., Nowak, B.F. and Cain, K.D. 2015. Assessment of immune response and protection against bacterial coldwater disease induced by a live-attenuated vaccine delivered orally or intraperitoneally to rainbow trout, Oncorhynchus mykiss (Walbaum). Aquaculture 446: 242–249
• Makesh, M., Sudheesh, S.S. and Cain, K.D. 2015. Systemic and mucosal immune response of rainbow trout to immunization with an attenuated Flavobacterium psychrophilum vaccine strain by different routes. Fish and Shellfish Immunology 44: 156-163
• Schubiger, C.B., Orfe, L.H., Ponnerassery, S.P., Cain, K.D., Shah, D.H. and Call, D.R. 2015. Entericidin is requisite for a probiotic treatment (Enterobacter C6-6) to protect trout from coldwater disease challenge. Applied and Environmental Microbiology 81:658 –665
• Egan, J.P., Johnson, R.D., Anders, P.J. and Cain, K.D. 2014. Initial Characterization of Embryonic Development in North American Burbot Lota lota maculosa. North American Journal of Aquaculture 77:1, 37-42
• Wiens, G.D., LaPatra, S.E., Welch, J.J., Rexroad 3rd, C., Call, D.R., Cain, K.D., LaFrentz, B.R., Vaisvil, B., Schmitt, D.P. and Kapatral, V. 2014. Complete genome of Flavobacterium psychrophilum strain CSF259-93 used to select rainbow trout for increased genetic resistance against bacterial cold water disease. Genome Announcements 2(5): e00889-14. doi:10.1128/genomeA.00889-14
• Plant, K. P., LaPatra, S.E., Call, D.R., and Cain, K.D. 2014. Attempts at validating a recombinant Flavobacterium psychrophilum gliding motility protein N as a vaccine candidate in rainbow trout, Oncorhynchus mykiss (Walbaum) against bacterial cold water disease. FEMS Microbiology Letters 358, 14–20
• Long, A., Fehringer, T.R., LaFrentz, B.R., Call, D.R. and Cain, K.D. 2014. Development of a waterborne challenge model for Flavobacterium psychrophilum. FEMS Microbiology Letters, 359, 154–160
• LaPatra, S.E., Fehringer, T.R. and Cain, K.D. 2014. A probiotic Enterobacter sp. provides significant protection against Flavobacterium psychrophilum in rainbow trout (Oncorhynchus mykiss) after injection by two different routes. Aquaculture, 433, 361–366
• Fehringer, T.R., Hardy, R.W. and Cain, K.D. 2014. Dietary inclusion of salmon testes meal from Alaskan seafood processing byproducts: Effects on growth and immune function of rainbow trout, Oncorhynchus mykiss (Walbaum). Aquaculture, 433, 34-39
• LaFrentz, B.R., LaPatra, S.E., Call, D.R., and Cain, K.D. 2014. Immunization of rainbow trout Oncorhynchus mykiss (Walbaum) with a crude lipopolysaccharide extract from Flavobacterium psychrophilum. Journal of Fish Diseases, 45, 476–483
• Ashton, N.K., Anders, P.J., Young, S.P. and Cain, K.D. 2014. Coded Wire and Passive Integrated Transponder Implantations in Juvenile Burbot. North American Journal of Fisheries Management, 34:2, 391-400
• Long, A., Call, D.R. and Cain, K.D. 2014. Investigation of the link between broodstock infection, vertical transmission, and prevalence of Flavobacterium psychrophilum in eggs and progeny of rainbow trout and coho salmon. Journal of Aquatic Animal Health, 26(2):66-77.
• Cain, K.D. and Polinski, M.P. 2014. Infectious Diseases of Coldwater Fish in Fresh Water. Chapter 3. In: Diseases and Disorders of Finfish in Cage Culture. Volume 2, (eds) Woo, P.T.K., and Bruno, D.W. CABI publishing, New York, NY. pp.60-113
• Ashton, N.K., Ireland, S.C. and Cain K.D. 2013. Artificial Marker Selection and Subsequent Tagging Evaluations with Juvenile Burbot. Transactions of the American Fisheries Society, 142:6, 1688-1698
• Barren, J.M. Jensen, N.R., Anders, P.J., Egan, J.P Ireland, S.C. and Cain K.D. 2013. Effects of stocking density on survival and yield of North American burbot reared under semi-intensive conditions. Transactions of the American Fisheries Society, 142:6, 1680-1687
• Holt, R.A., Bertolini, J., Cain, K. and Long, A. 2013. Coldwater Disease. In: Fish Health Section Blue Book; Suggested procedures for the detection and identification of certain finfish and shellfish pathogens. Chapter 2.2, American Fisheries Society (Invited book chapter)
• Woo, P.T.K. and Cain K.D. 2013. Editors. Current and Emerging Diseases/Disorders of Fish in Aquaculture. Special Issue: Journal of Aquaculture Research and Development, (International Open Access) ISSN:2155-9546
• Barren, J.M., Jensen, N.R., Anders, P.J., Egan, J.P., Ireland, S.C. and Cain, K.D. 2013. Suppression of cannibalism during larviculture of burbot (Lota lota maculosa) through size grading. North American Journal of Aquaculture 75:4, 556-561
• Valdenegro-Vega, V.A., Crosbie, P., Vincent, B., Cain, K.D., and Nowak B.F. 2013. Effect of immunization route on mucosal and systemic immune response in Atlantic salmon (Salmo salar). Veterinary Immunology and Immunopathology 151(1-2):113-23
• Long, A., Fehringer, T.R, Swain, M.A., LaFrentz, B.R., Call, D.R. and Cain K.D. 2013. Enhanced efficacy of an attenuated Flavobacterium psychrophilum strain cultured under iron- limited conditions. Fish and Shellfish Immunology, 35: 1477-1482
• Polinski, M., Jensen, N., Foltz, J., Ireland, S. and Cain, K.D. 2013. Hydrogen peroxide treatments administered to hatchery reared burbot (Lota lota): assessing treatment regimes from embryonic development through juvenile rearing. North American Journal of Aquaculture, 75:1 50-56
• Burbank, D.R., LaPatra, S.E., Fornshell, G. and Cain, K.D. 2012. Isolation of bacterial probiotics candidates from the gastrointestinal (GI) tract of rainbow trout and screening for in vitro inhibitory activity to Flavobacterium psychrophilum. Journal of Fish Diseases, 35:11 809-816
• Gliniewicz, K, KP Plant, SE LaPatra, BR LaFrentz, K Cain, KR Snekvik and DR Call. 2012. Comparative proteomic analysis of virulent and rifampicin attenuated Flavobacterium psychrophilum. Journal of Fish Diseases, 35(7):529-39
• Snyder, S, Barrows, R., Hill, R., Gaylord, G., Overturf, K. Cain, K.D., and Hardy, R. 2012. Effects of carnosine supplementation to an all-plant protein diet for rainbow trout (Oncorhynchus mykiss). Aquaculture, 338-341, 72-81
• Foltz, J.R., Jensen, N.R., Polinski, M.P., Ireland, S.C. and Cain, K.D. 2012. Characterization of egg development by catheterization and consequences for delaying egg fertilization in hatchery reared burbot (Lota lota) North American Journal of Aquaculture, 74:3 408-412
• Long, A., Polinski, M.P., Call, D.R., and Cain, K.D. 2012. Validation of Diagnostic Assays to Screen Broodstock for Flavobacterium psychrophilum infections. Journal of Fish Diseases, 35, 407-419
• Barren, J.M., Jensen, M.R., Anders, P.J., Egan, J.P., Ireland, S.C. and Cain, K.D. 2012. Effects of temperature on the intensive culture performance of larval and juvenile North American burbot (Lota lota maculosa). Aquaculture, 364-365, 67-73
• Burbank, D.R., Shah, D.H., LaPatra, S.E., Fornshell, G. and Cain, K.D. 2011. Enhanced resistance to coldwater disease following feeding of probiotic bacterial strains to rainbow trout (Oncorhynchus mykiss). Aquaculture, 321, 185-190
• LaFrentz, B.R., LaPatra, S.E., Call, D.R., Wiens, G.D., and Cain, K.D. 2011. Identification of Immunogenic proteins within distinct molecular mass fractions of Flavobacterium psychrophilum. Journal of Fish Diseases, 34, 823-830
• Lloyd, S.J., LaPatra, S.E., Snekvik, K.R., Cain, K.D., and Call, D.R. 2011. Quantitative PCR demonstrates a positive correlation between a Rickettsia-like organism and severity of strawberry disease lesions in rainbow trout (Oncorhynchus mykiss). Journal of Fish Diseases, 34, 701-709
• Jensen, N.R., Anders, P.J., Hoffman, C.A., Porter, L.S., Ireland, S.C., and Cain, K.D. 2011. Performance and macronutrient composition of Age-0 burbot fed four diet treatments. North American Journal of Aquaculture, 73:3, 360-368
• Paragamian, V.L, Laude, C., Cain, K.D., Barron, J.M., and Jensen,N. 2011. A novel experiment of rearing burbot larvae in cages. Journal of Applied Ichthyology. 27 (1), 16–21
• Neufeld, M.D., Cain, K., Jensen, N., Ireland, S.C., and Paragamian, V.L. 2011. Movement of Lake Origin Burbot Reared in a Hatchery Environment and Released into a Large River. North American Journal of Fisheries Management 31, 56-62
• Plant, K.P., LaPatra, S.E., Call, D.R., and Cain, K.D. 2011. Immunization of rainbow trout (Oncorhynchus mykiss) with Flavobacterium psychrophilum proteins elongation factor-Tu, SufB Fe-S assembly protein and ATP synthase. Journal of Fish Diseases 34, 247-250
• Polinski, M.P., Drennan, J.D., Batts, W.N., Ireland, S.C., Cain, K.D. 2010. Establishment of a cell line from burbot Lota lota with characterization of susceptibility to IHNV, IPNV and VHSV. Diseases of Aquatic Organisms 90, 15-23
• Polinski, M.P., Fehringer, T.R., Johnson, K.A., Snekvik, K.R., LaPatra, S.E., LaFrentz, B.R., Ireland, S.C., Cain, K.D. 2010. Characterization of susceptibility and carrier status of burbot to IHNV, IPNV, Flavobacterium psychrophilum, Aeromonas salmonicida, and Renibacterium salmoninarum. Journal of Fish diseases 33, 559-570
• Polinski, M.P., Johnson, K.A., Ireland, S.C., Jensen, N.R., and Cain, K.D. 2010. Assessment of formalin and hydrogen peroxide use during egg incubation of burbot (Lota lota maculosa). North American Journal of Aquaculture 72, 111-117
• LaFrentz, B.R., LaPatra, S.E., Call, D.R., Wiens, G.D., and Cain, K.D. 2009. Proteomic analysis of Flavobacterium psychrophilum cultured in vivo and in iron-limited media. Diseases of Aquatic Organisms 87: 171-182
• Cain, K.D and Swan, C.M. 2010. Barrier Function and Immunology. “The Multifunctional Gut of Fish” Elsevier Inc., (Invited book chapter ), Fish physiology vol: 30, 112-134
• Lindstrom, N.M., Call, D.R., House, M.L., Moffitt, C.M., and Cain, K.D. 2009. A quantitative enzyme-linked immunosorbent assay (ELISA) and filtration-based fluorescent antibody test (FAT) as potential tools to screen broodstock for Flavobacterium psychrophilum infection. Journal of Aquatic Animal Health 21(1): 43-56
• Plant, K.P., LaPatra, S.E., and Cain, K.D. Vaccination of rainbow trout (Oncorhynchus mykiss) with recombinant and DNA vaccines produced to Flavobacterium psychrophilum heat shock proteins 60 and 70. Journal of Fish Diseases 32(6): 521-534
• Lloyd, S.J., Snekvik, K.R., St-Hilaire, S., LaPatra, S.E., Cain, K.D., and Call, D.R. 2008. Strawberry Disease lesions in rainbow trout (Oncorhynchus mykiss) are closely associated with a Rickettsia-like organism. Diseases of Aquatic Organisms 82: 111-118
• LaFrentz, B.R., LaPatra, S.E., Call, D.R., and Cain, K.D. 2008. Development and characterization of rifampicin resistant Flavobacterium psychrophilum strains and their potential as live attenuated vaccine candidates. Vaccine 26 (2008) 5582–5589

For a complete list of publications, please see Kenneth Cain's CV

• Distinguished Professor Award, University of Idaho, rank granted 2021
• Distinguished Service Award, Idaho Chapter AFS, Aquaculture Committee, Chair 2004-2020
• Excellence in Research and Creative Activity Award, University of Idaho 2020
• Nominated (by Research Office) as Fellow for National Academy of Inventors, 2018, 2019
• Mid-Career Presidential Award, University of Idaho 2013-2014
• Innovation Award for licensed technology, 2012
• Innovation Award for Issued Patent “Vaccines for Diseases of Fish”, 2010
• Innovation Award for Technology Licensed (Cain/ImmunoPrecise Antibodies, Ltd), 2009
• Best Professional Poster presentation (Idaho Chapter AFS meeting), 2009

Article for Waterlines (published by the Western Regional Aquaculture Center), 2008, 2010
Presented research overview at Idaho Aquaculture Association annual meeting, 2008, 2010